Skip to main content Skip to Search Box

Definition: Intron from Encyclopedia of Cancer
Definition

Noncoding DNA which separates neighboring exons in a gene. During gene expression, introns are transcribed into RNA but then intron sequences are removed from the pre-mRNA by splicing. Intervening sequence that is removed from the pre-mRNA by the splicing reaction.

See also Pre-mRNA Splicing


intron

From The Hutchinson Unabridged Encyclopedia with Atlas and Weather Guide
In genetics, a stretch of DNA that interrupts the coding parts ( exons ) of a gene but apparently carries no genetic information. Introns, discovered in 1977, are at first transcribed into messenger RNA (mRNA) but removed before translation . While some introns harbour a catalytic activity involving their own excision from the mRNA, in most cases their function is unknown. Introns are very common in the genomes of many eukaryotes , and particularly in mammals and in flowering plants, where they often account for many more base pairs than the coding exons. In the human genome, for instance, exons make up 1.1% of the total length, and introns 24% (the remainder is referred to as intergenic DNA). Initially, introns were considered part of the widespread phenomenon of junk DNA , which was believed to be old DNA no longer useful to the cell. With the growing understanding of genomes , however, scientists have increasingly found functional elements within introns and other ‘junk’ elements. …
585 results

Full text Article intron homing (in bacteria)

From Dictionary of Microbiology & Molecular Biology
The process in which introns (of either group I or group II) spread, in replicative fashion, to allelic intron-less genes. The mechanism of intron homing differs in the two types of intron. Intron homing in group I introns is initiated when a DNA endonuclease ( homing endonuclease ), encoded within…
| 239 words
Key concepts:

Full text Article intron

From The Hutchinson Unabridged Encyclopedia with Atlas and Weather Guide
In genetics, a stretch of DNA that interrupts the coding parts ( exons ) of a gene but apparently carries no genetic information. Introns, discovered in 1977, are at first transcribed into messenger RNA (mRNA) but removed before translation . While some introns harbour a catalytic activity involving…
| 265 words
Key concepts:

Full text Article intron

From Penguin Dictionary of Biology
DNA sequence lying within a coding sequence, but not usually encoding cell product, and resulting in so-called ‘split-genes’ (see Fig. 60 ); almost universal in eukaryotic genes (but not INTERFERON genes), where on average there are ten per gene; but few examples of prokaryotic introns. Usually…
| 404 words
Key concepts:

Full text Article Intron Homing

From Brenner's Encyclopedia of Genetics
(a) Group I intron homing pathway: The...
Abstract Group I introns typically move by a DNA-based mobility mechanism that involves homologous recombination. By contrast, mobile group II introns can integrate into DNA by the reverse splicing of its lariat RNA transcript into a target site; the inserted intron RNA serves as a template for DNA…
| 3,461 words , 4 images
Key concepts:

Full text Article Introns and Exons

From Brenner's Encyclopedia of Genetics
An intron (or ‘intervening sequence’) is a segment of RNA excised from a gene transcript, with concomitant ligation of flanking segments called ‘exons’. This process of excision and ligation, known as ‘splicing’, is one of several posttranscriptional processing steps that may occur prior to…
| 933 words
Key concepts:

Full text Article intron

From Collins Dictionary of Medicine
| 46 words

Full text Article intron

From The New Dictionary of Cultural Literacy, Houghton Mifflin
| 33 words
Key concepts:

Full text Article intron

From The American Heritage(R) Dictionary of the English Language
| 39 words
Key concepts:

Full text Article intron

From Dictionary of Developmental Biology and Embryology
| 43 words
Key concepts:

Full text Article intron

From Science Encyclopedia: Encyclopedia of Chemistry
| 56 words
Key concepts:
Mind Map

Stack overflow
More Library Resources